Case Studies

The Elements

Case Studies

This section contains case studies relating to the 12 elements. Case studies are listed alphabetically below but may also be accessed by theme by looking under each element heading listed under ‘The Elements’. We welcome suggestions for case studies.

A “One Health” Approach to Address Emerging Zoonoses: The HALI Project in Tanzania

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7/10/2010 4:48:21 PM

This document describes the One Health project in rural Tanzania, designed to find solutions to diseases that have arisen at the human–animal–environment interface, by investigating the impact of zoonotic disease on the health and livelihoods of rural Tanzanians living in the water-limited Ruaha ecosystem.
A novel anti-influenza copper oxide containing respiratory face mask

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1/07/2010 12:54:04 PM

While protective respiratory face masks protect people from vapor drops carrying viruses and other infectious pathogens, incorrect use and disposal may actually increase the risk of pathogen transmission. This study assesses the efficacy of using copper oxide in respiratory protective face masks to significantly reduce the risk of hand or environmental contamination, and consequent infection. This study was funded by Cupron Scientific, a company that specialises in research and development of medical devices using copper oxide as the active ingredient.
A Novel Peptide ELISA for Universal Detection of Antibodies to Human H5N1 Influenza Viruses

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30/06/2011 11:15:12 AM

A team at the National University of Singapore, Velumani et al has developed a peptide enzyme-linked immunosorbent assay (ELISA) to detect infection with H5N1 avian influenza in humans and animals based an H5 HA epitope that is conserved 100% in human H5N1 isolates and 97% in avian isolates. The team evaluated the sensitivity and specificity of the assay using chicken antisera to H5N1 viruses from divergent clades and other influenza viruses, as well as human sera from patients infected with H5N1 or seasonal influenza. The assay detected antibodies to H5N1 more accurately than hemagglutinin inhibition, immunofluorescence assay, and immunodot blot tests.
Absence of 2009 Pandemic H1N1 Influenza A Virus in Fresh Pork

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28/01/2010 12:05:17 PM

The emergence of the pandemic H1N1 2009 influenza A virus in humans and subsequent discovery that it was of swine influenza virus lineages raised many food safety concerns. If swine were to become infected with the pandemic virus would the meat be contaminated with virus and be a potential source of human infection? This case study addresses these issues.
Addressing the HPAI threat in Sri Lanka

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17/04/2009 12:40:49 PM

An article from the Winter 2009 issue of the One Health Newsletter on the united approach by the veterinary and human health sectors in Sri Lanka to the threat of HPAI. The Newsletter is published by the One Health Initiative.
Agriculture-Associated Diseases: Adapting Agriculture to Improve Human Health

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22/02/2011 3:15:51 PM

Agriculture and health are intimately linked. Many diseases have agricultural roots—food-borne diseases, water associated diseases, many zoonoses, most emerging infectious diseases, and occupational diseases associated with agrifood chains. As agriculture-associated diseases occur at the interface of human health, animal health, agriculture, and ecosystems, addressing them often requires systems-based thinking and multi-disciplinary approaches. MacDermott and Grace discuss this thinking.
Animal Migration and Infectious Disease Risk

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25/01/2011 2:41:20 PM

New research has also shown that migration allows hosts to escape from infected habitats, reduces disease levels when infected animals do not migrate successfully, and may lead to the evolution of less-virulent pathogens. Migratory demands can also reduce immune function, with consequences for host susceptibility and mortality. Studies of pathogen dynamics in migratory species and how these will respond to global change are urgently needed to predict future disease risks for wildlife and humans alike.
Assessment of Smallholder Indigenous Poultry Producer Viability in Thailand

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11/08/2009 10:53:59 AM

This Pro-Poor working paper discusses a survey-based assessment of the viability of indigenous poultry producers after HPAI in Thailand. Backyard smallholder production remains ubiquitous among the country’s rural poor majority and this group has been adversely affected by both HPAI outbreaks and control measures taken in response to them. This paper offers guidance for the design of more socially-effective responses to HPAI and other animal disease risks.
Avian influenza A (H5N1) in humans: lessons learned from Egypt

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18/06/2010 11:49:41 AM

This study, recently published in Eurosurveillance, examines the recorded cases of avian influenza in humans and explains the epidemilogical significance of the findings.
Avian influenza A(H5N1) in humans: new insights from a line list of World Health Organization confirmed cases, September 2006 to August 2010

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31/08/2011 11:01:20 AM

Ressearchers from the Robert Koch Institute, Department for Infectious Disease Epidemiology, Respiratory Infections Unit Germany showed that data from the public domain yield important epidemiological information on the global AI situation. They say that the establishment of a line list is a prerequisite to such evaluations as it might enhance our understanding of AI in humans and permit the rapid detection of changes in its epidemiology with implications for human health.

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